De novo genome assemblies
De novo genome assemblies
Improved genomic selection and breeding utilizing high quality reference genomes
The Molecular Genomics group assists in the development of cultivars with superior quality through practical application of high throughput sequencing and genotyping technologies. The team continuously scouts for novel developments in these fields and evaluates the most promising of these technologies for application by the shareholder or in shareholder specific applied projects. Currently, one of the main focus points in the molecular breeding (r)evolution is the increased output and read length of sequencing platforms. The Molecular Genomics group anticipates on these developments by optimizing protocols for High Throughput DNA isolation and High Throughput Sequence library preparation. In addition, the isolation of pure HMW DNA is a focus point, as this is essential to benefit optimally from the long read sizes of novel sequencing technologies. In addition, novel genotyping approaches and optimizations in turn-around time are continuously being evaluated for application in a.o. Genomic Selection programs.
The bioinformatics department at Genetwister applies information technology to the research performed at the company. Within this department, expertise in the fields of molecular biology, information technology, statistics and programming is combined to support gene discovery, breeding, metabolic engineering and diagnostics. An important activity is visualization of data, as this will help the other departments and our clients to convert the results into applications. The department has developed tools for analyzing sequencing data, SNP discovery (CROPaware™ software), genome analysis and analysis of expression data from custom oligoarrays. Furthermore, databases are designed to store and analyze biological data sets with controlled access for the clients through web applications.
The group Genetics and Breeding aims to enhance the breeding craft of our shareholders with a focus on providing breeding tools based on state-of-the-art methodology in the field of statistical genetics.
In the Software Development Group we contribute to the research activities in Genetwister by applying computer science principles and practices.
We are an innovative Dutch biotechnology company, with an international position in commercially applied biotechnology of agri- and horticultural crops. Genetwister is your partner in accelerating the breeding of your crop.
Genetwister works to provide cutting edge technologies to five breeding companies to strengthen their leading positions in the field.
Improved genomic selection and breeding utilizing high quality reference genomes
In Genetwister we develop tools using distribute computing models and technologies like Spark and Hadoop.
Discovery of markers in all plant species by next-generation sequencing for accelerated plant breeding
CROPaware – A web based software platform for breeding and genomics data management.
To interconnect different knowledge domains we use different semantic web technologies...
Genomic Selection was implemented at GT
With increasing sample numbers comes the need for automating the most valuable and applied protocols at Genetwister.
With increasing sample numbers and marker panel sizes, it is valuable to increase the throughput of sequencing and genotyping procedures. Genetwister develops cost-effective methods and applies available methods for allowing high-throughput genomics.
With the increasing demands for DNA molecule size and purity on the newest long read sequencing platforms comes the need for developing new protocols for DNA isolation from different biological sources in the laboratory at Genetwister.
High parallel computing version of a sequence alignment application