With increasing sample numbers and marker panel sizes, it is valuable to increase the throughput of sequencing and genotyping procedures. Genetwister develops cost-effective methods and applies available methods for allowing high-throughput genomics.
Tailored marker selection allowing for genotyping regardless of species, genome size and ploidy level.
At Genetwister, tools are developed using distributed computing models and technologies like Spark and Hadoop.
To interconnect different knowledge domains, we use different semantic web technologies.
Using state-of-the-art long read sequencing technologies, Genetwister builds high quality genome assemblies of novel species and obtains long-range genomic information such as haplotypes and structural variants.
Genetwister investigates new precision phenotyping methods to integrate phenotypic data into genetic models to support breeding
Advanced statistical models are needed to increase the power to discover (new) associations between genetic and phenotypic variation.
Appropriate experimental design and data analysis of breeding trials are essential. Genetwister offers assistance in the experimental design, taking into account all practical considerations of the breeding program.
With increasing sample numbers comes the need for automating the most valuable and most often applied protocols at Genetwister.
Discovery of markers in all plant species by next-generation sequencing for accelerated plant breeding