The availability of a high-quality, chromosome-level reference genome accelerates breeding programs. A reference genome assembled to large scaffolds or even full-length chromosomes reveals the genome architecture as well as locations of specific genes and markers. Insight into gene order allows QTL analyses to be performed without the need of a physical map. Additionally, questions involving structural variant detection can be answered, facilitating prediction of recombination frequencies along the genome. A high-quality reference genome is also a valuable addition to breeding programs involving commercial varieties that lack specific traits that are available in wild germplasm.

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Other innovations

Genotyping array design
Genotyping array design

Genotyping array design

Tailored marker selection allowing for genotyping regardless of species, genome size and ploidy level.

14 Mar. 2021 View project
Association analysis
Association analysis

Association analysis

Advanced statistical models are needed to increase the power to discover (new) associations between genetic and phenotypic variation.

1 Mar. 2021 View project
Semantic Web
Semantic Web

Semantic Web

To interconnect different knowledge domains, we use different semantic web technologies.

14 Mar. 2021 View project
Genomic Selection
Genomic Selection

Genomic Selection

Genomic selection (GS) accelerates achieving genetic gain through shorter breeding cycles and is an alternative to marker-assisted selection. Genetwister implements new breeding schemes and methods that integrate GS for crop improvement.

14 Mar. 2021 View project
Experimental Design
Experimental Design

Experimental Design

Appropriate experimental design and data analysis of breeding trials are essential. Genetwister offers assistance in the experimental design, taking into account all practical considerations of the breeding program.

1 Mar. 2021 View project
Lab automation
Lab automation

Lab automation

With increasing sample numbers comes the need for automating the most valuable and most often applied protocols at Genetwister.

14 Mar. 2021 View project
Long Read Sequencing
Long Read Sequencing

Long Read Sequencing

Using state-of-the-art long read sequencing technologies, Genetwister builds high quality genome assemblies of novel species and obtains long-range genomic information such as haplotypes and structural variants.

14 Mar. 2021 View project