Sequence alignment is a commonly used tool in bioinformatics for different applications. In order to increase the performance of these tools (e.g. BLAST and the different versions of it) in terms of execution time, the Software Development Group at Genetwister created a BLAST based implementation which can run in a Spark cluster using HDFS as file system support.
Long Read Sequencing
Using the state-of-the-art technologies such as long read sequencing technologies, Genetwister is able to build high quality genome assemblies of novel species, and obtain long range genomic information such as haplotypes and structural variants.