Sequence alignment is a commonly used tool in bioinformatics for different applications. In order to increase the performance of these tools (e.g. BLAST and the different versions of it) in terms of execution time, the Software Development Group at Genetwister created a BLAST based implementation which can run in a Spark cluster using HDFS as file system support.
High Molecular Weight DNA isolation
With the increasing demands for DNA molecule size and purity on the newest long read sequencing platforms, comes the need for developing new protocols for DNA isolation from different biological sources in the laboratory at Genetwister.