Experimental Design

With increasing sample numbers and marker panel sizes, it is valuable to increase the throughput of sequencing and genotyping procedures. Genetwister develops cost-effective methods and applies available methods for allowing high-throughput genomics.

High performance BLAST implementation adapted to run in Spark clusters.

Genomic selection (GS) accelerates achieving genetic gain through shorter breeding cycles and is an alternative to marker-assisted selection. Genetwister implements new breeding schemes and methods that integrate GS for crop improvement.

Using state-of-the-art long read sequencing technologies, Genetwister builds high quality genome assemblies of novel species and obtains long-range genomic information such as haplotypes and structural variants.

High-quality reference genome assemblies improve Genomic Selection and breeding

Discovery of markers in all plant species by next-generation sequencing for accelerated plant breeding

Acceleration and cost reduction in plant breeding with improved genotype/phenotype relations, utilizing linked variants.

To interconnect different knowledge domains, we use different semantic web technologies.

With increasing sample numbers comes the need for automating the most valuable and most often applied protocols at Genetwister.

Tailored marker selection allowing for genotyping regardless of species, genome size and ploidy level.