In a state-of-the-art laboratory with high-end equipment and experienced personnel, Genetwister constantly updates and adapts its protocols to the changing needs of long read sequencing and optical mapping platforms. Special care is taken to reach the proper DNA molecule size and purity levels. In addition, Genetwister is involved in scaling up the number of samples which are processed for high molecular weight DNA isolations. These high-throughput protocols in combination with lab automation, are useful for haplotyping entire mapping populations, increasing the accuracy of genotyping and marker-assisted breeding.
Advanced statistical models are needed to increase the power to discover (new) associations between genetic and phenotypic variation