High-throughput sequencing and genotyping

Discovery of markers in all plant species by next-generation sequencing for accelerated plant breeding

Genetwister investigates new precision phenotyping methods to integrate phenotypic data into genetic models to support breeding

Acceleration and cost reduction in plant breeding with improved genotype/phenotype relations, utilizing linked variants.

With increasing sample numbers comes the need for automating the most valuable and most often applied protocols at Genetwister.

At Genetwister, tools are developed using distributed computing models and technologies like Spark and Hadoop.

High performance BLAST implementation adapted to run in Spark clusters.

To interconnect different knowledge domains, we use different semantic web technologies.

Advanced statistical models are needed to increase the power to discover (new) associations between genetic and phenotypic variation.

Using the state-of-the-art technologies such as long read sequencing technologies, Genetwister is able to build high quality genome assemblies of novel species, and obtain long range genomic information such as haplotypes and structural variants.

High-quality reference genome assemblies improve Genomic Selection and breeding