High Molecular Weight DNA isolation

High parallel computing version of a sequence alignment application.

With increasing sample numbers and marker panel sizes, it is valuable to increase the throughput of sequencing and genotyping procedures. Genetwister develops cost-effective methods and applies available methods for allowing high-throughput genomics.

To interconnect different knowledge domains, we use different semantic web technologies.

At Genetwister, tools are developed using distributed computing models and technologies like Spark and Hadoop.

Appropriate experimental design and data analysis of breeding trials are essential. Genetwister offers assistance in the designing of experiments, taking into account the breeding program’s practical considerations.

Genetwister investigates new methods to integrate phenotypic data into genetic models to support breeding

Improved genomic selection and breeding utilizing high quality reference genomes

Using the state-of-the-art technologies such as long read sequencing technologies, Genetwister is able to build high quality genome assemblies of novel species, and obtain long range genomic information such as haplotypes and structural variants.

Tailored marker selection allowing for genotyping regardless of species, genome size and ploidy level.

Advanced statistical models are needed to increase the power to discover (new) associations between genetic and phenotypic variation