The main focus of the bioinformatics team is genomic data analyses that support breeding efforts. To provide a solid backbone for downstream data processing, we assemble high-quality reference genomes and transcriptomes that are supported by structural and functional annotation. This is often supplemented with studies of diversity such as variant discovery and inference of phylogenies. Moreover, we provide analyses geared towards specific questions such as quantitative transcriptomics, haplotyping and design of various genotyping platforms.

Our innovations

Haplotype discovery
Haplotype discovery

Haplotype discovery

Acceleration and cost reduction in plant breeding with improved genotype/phenotype relations, utilizing linked variants.

14 Mar. 2018 View project
Genomic Selection
Genomic Selection

Genomic Selection

Genomic selection (GS) is an alternative to marker-assisted selection, which can accelerate the genetic gain through shorter breeding cycles. Genetwister is implementing new breeding schemes and methods that integrate GS for crop improvement.

14 Mar. 2018 View project
High-throughput sequencing and genotyping
High-throughput sequencing and genotyping

High-throughput sequencing and ...

With increasing sample numbers and marker panel sizes, it is valuable to increase the throughput of sequencing and genotyping procedures. Genetwister develops cost-effective methods and applies available methods for allowing high-throughput genomics.

4 Apr. 2018 View project
High Molecular Weight DNA isolation
High Molecular Weight DNA isolation

High Molecular Weight DNA isolation

With the increasing demands for DNA molecule size and purity on the newest long read sequencing platforms, comes the need for developing new protocols for DNA isolation from different biological sources in the laboratory at Genetwister.

14 Mar. 2018 View project
Long Read Sequencing
Long Read Sequencing

Long Read Sequencing

Using the state-of-the-art technologies such as long read sequencing technologies, Genetwister is able to build high quality genome assemblies of novel species, and obtain long range genomic information such as haplotypes and structural variants.

14 Mar. 2018 View project
Association analysis
Association analysis

Association analysis

Advanced statistical models are needed to increase the power to discover (new) associations between genetic and phenotypic variation

1 Aug. 2018 View project
Genotyping array design
Genotyping array design

Genotyping array design

Tailored marker selection allowing for genotyping regardless of species, genome size and ploidy level.

14 Mar. 2018 View project