The Bioinformatics team applies state of the art information technology in research projects for our customers. We combine our expertise in the fields of molecular biology, information technology, statistics and programming to support genetic marker development, gene discovery, breeding for complex traits and identify lead genes for trait improvement via classical or novel breeding technologies. Visualization of vast amounts of data is an important aspect of our work, as this helps our scientists and customers to use the results of research projects to improve crops.

The main focus of the bioinformatics team is on genomic data analyses that support breeding efforts. To provide a solid backbone for downstream data processing, we assemble high-quality reference genomes and transcriptomes and perform structural and functional annotation. This is often supplemented with studies of diversity such as variant discovery and inference of phylogenies. Moreover, we conduct analyses geared towards specific questions such as quantitative transcriptomics, haplotyping and design of various genotyping assays.

Our innovations

Semantic Web
Semantic Web

Semantic Web

To interconnect different knowledge domains, we use different semantic web technologies.

14 Mar. 2021 View project
Experimental Design
Experimental Design

Experimental Design

Appropriate experimental design and data analysis of breeding trials are essential. Genetwister offers assistance in the experimental design, taking into account all practical considerations of the breeding program.

1 Mar. 2021 View project
Haplotype discovery
Haplotype discovery

Haplotype discovery

Acceleration and cost reduction in plant breeding with improved genotype/phenotype relations, utilizing linked variants.

14 Mar. 2021 View project
High-throughput sequencing and genotyping
High-throughput sequencing and genotyping

High-throughput sequencing and ...

With increasing sample numbers and marker panel sizes, it is valuable to increase the throughput of sequencing and genotyping procedures. Genetwister develops cost-effective methods and applies available methods for allowing high-throughput genomics.

4 Feb. 2021 View project
Association analysis
Association analysis

Association analysis

Advanced statistical models are needed to increase the power to discover (new) associations between genetic and phenotypic variation.

1 Mar. 2021 View project
Lab automation
Lab automation

Lab automation

With increasing sample numbers comes the need for automating the most valuable and most often applied protocols at Genetwister.

14 Mar. 2021 View project
Marker discovery
Marker discovery

Marker discovery

Discovery of markers in all plant species by next-generation sequencing for accelerated plant breeding

28 Feb. 2021 View project