Genomics

Advanced statistical models are needed to increase the power to discover (new) associations between genetic and phenotypic variation.

With increasing sample numbers comes the need for automating the most valuable and most often applied protocols at Genetwister.

High performance BLAST implementation adapted to run in Spark clusters.

Genetwister investigates new precision phenotyping methods to integrate phenotypic data into genetic models to support breeding

Discovery of markers in all plant species by next-generation sequencing for accelerated plant breeding

Tailored marker selection allowing for genotyping regardless of species, genome size and ploidy level.

With increasing sample numbers and marker panel sizes, it is valuable to increase the throughput of sequencing and genotyping procedures. Genetwister develops cost-effective methods and applies available methods for allowing high-throughput genomics.

Appropriate experimental design and data analysis of breeding trials are essential. Genetwister offers assistance in the experimental design, taking into account all practical considerations of the breeding program.

High-quality reference genome assemblies improve Genomic Selection and breeding

Genomic selection (GS) accelerates achieving genetic gain through shorter breeding cycles and is an alternative to marker-assisted selection. Genetwister implements new breeding schemes and methods that integrate GS for crop improvement.